EMSAM a flop? No kidding!

[Anasazi23]

This seems to be a surprise to noone but themselves.

http://blogs.wsj.com/health/2007/05/01/bristol-myers-exec-dishes-on-depression-patch/

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Members don't see this ad.

 

[Therapist4Chnge]

Color me shocked....SHOCKED!



-t

 

[whopper]

I'd consider giving it--if an SSRI failed.

 

[MBK2003]

There's been an extensive thread about this on our psychopharm listserv. The general impression is that EMSAM is NOT a treatment for treatment refractory depression, and (my favorite quote) "EMSAM is very effective at producing one result in all my patients on it - poverty."

MBK2003

 

[Therapist4Chnge]

Not that it matters much now.....

1. How often have you seen skin irritation?
2. How were the s/e for the 9 and 12 patches? (All I kept hearing and reading was about the 'wonders' of the 6mg)

-t

 

[Anasazi23]

I'd consider giving it--if an SSRI failed.

I inherited a couple patients on it in the clinic.
I don't think it'll accomplish anything that I can't achieve with a tricyclic or an augmented ssri. I'd have to go through most of my gamut of augmenting strategies, which are a lot, to get to this....unless the patient was interested in it as a higher option.

Going over the 6mg is almost mandatory, and also brings in the dietary restriction, which is a real PITA for some patients.

Still, I think that overall, the more methods of delivery we have available to us, the better. There are times when we need liquid ssri's and the like.

 

[Therapist4Chnge]

I think delivery systems can definitely improve....though I wasn't really sure why they chose try an MAOI patch....I'd think that would be a bottom of the list choice. Pts in general have a hard enough time with med compliance, what makes them think they will actually change their dietary intake?

I'd like to see more dissolveable gels (like the Listerine tabs)....I wonder if anyone would consider them for pre-existing meds?

-t

 

[positivepsych]

I think delivery systems can definitely improve... I'd like to see more dissolveable gels (like the Listerine tabs)....I wonder if anyone would consider them for pre-existing meds?
-t

If the drug companies won't come up with innovative delivery systems, then entrepreneurial chemists will:

http://www.onmarijuana.com/2007/03/21/thc-breathstrips-are-here-and-they-are-amazing/

 

[whopper]

Still, I think that overall, the more methods of delivery we have available to us, the better. There are times when we need liquid ssri's and the like.

Agree.

I haven't even prescribed one patient on this thing yet, but I'm glad there is a transdermal delivery system just in case.

 

[Therapist4Chnge]

If the drug companies won't come up with innovative delivery systems, then entrepreneurial chemists will:

http://www.onmarijuana.com/2007/03/21/thc-breathstrips-are-here-and-they-are-amazing/

I just read an article in Rolling Stone not too long ago that talked about those!



-t