USMLE Extent of genetic counseling/probability questions?

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Daitong

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Hi all,

So our school invests a few days pretty heavily on genetic counseling and related issues: for example we use Bayes' theorem to calculate that the probably a child will have a duchenne's MD assuming a 1/3 de novo mutation rate etc.

I was wondering if this is even remotely low yield or just completely untested? I'm not referring to basic carrier autodom/autorecessive etc nor am I talking about epidemiology (sensitivity,specificity), but more advanced mathematics (Bayes') to estimate the probably of a child having disease?

Please let me know- Thanks!

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You may use Bayes on certain questions (like asking for post-test probability) but you can easily solve these with other simple methods. So, for Step 1, Bayes theorem (and even other advanced biostat topics) are low- to no-yield. If you are doing fine with UW questions, then you should be good to go. My thoughts.
 
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