what is the difference between humoral and cell mediated immunity? I understand what is out of the Kaplan book and various other study books with regards to the different antibodies and the the T lymphocytes and B lymphocytes and the lymphocyte precursors with primary responses and memory responses...but in terms of humoral vs. cell mediated, what do those even mean? thanks. Also, could someone please explain the histamine response with allergies? Like, why your nose runs...that whole thing, because it just has not sunk in yet...Thanks.