hemolytic anemia in beta-thalassemia?

Discussion in 'Step I' started by MudPhud20XX, 09.19.14.

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  1. MudPhud20XX

    MudPhud20XX 2+ Year Member

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    I didn't think you would see hemolytic anemia in beta thalassemia, but I just did a UW question that you had to know this. As far as I know when it comes to hemolytic anemia, I always think of some kinds of autoimmune, PNH, G6PD def etc....

    Can anyone explain why you would get hemolytic anemia in beta-thalassemia. I don't really recall this from Pathoma either. What am I missing here? Thank you for the help.
     
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  3. SBR249

    SBR249 7+ Year Member

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    Robbins has a very concise explanation for this on pg. 414 of the 9th edition:

     
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