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heparin vs warfarin

Discussion in 'Medical Students - MD' started by coconut lime, Apr 20, 2004.

  1. coconut lime

    coconut lime Senior Member
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    i understand the theoretical differences between the 2, but can someone explain how the clinical applications of each one differ? thanks!
     
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  3. idq1i

    Physician 15+ Year Member

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    heparin vs. warfarin

    IV only vs Oral

    Quick action vs. Delayed action
     
  4. coconut lime

    coconut lime Senior Member
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  5. BassDominator

    BassDominator Senior Member
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    All depends on why you need anticoagulation....

    Some examples:
    1. DVT treatment: start with heparin until therapeudic PTT, then add coumadin until therapeudic INR, then send patient home on oral coumadin (remember you need heparin to start coumadin because protein C/S get blocked first and they are anticoagulants!)
    2. Cardiopulmonary bypass surgery: you want heparin because it starts acting fast and can be reversed quickly with protamine. you don't want the patient clotting on the machine, but you also don't want him/her bleeding when they come off bypass
     

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