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coconut lime

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i understand the theoretical differences between the 2, but can someone explain how the clinical applications of each one differ? thanks!
 

BassDominator

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All depends on why you need anticoagulation....

Some examples:
1. DVT treatment: start with heparin until therapeudic PTT, then add coumadin until therapeudic INR, then send patient home on oral coumadin (remember you need heparin to start coumadin because protein C/S get blocked first and they are anticoagulants!)
2. Cardiopulmonary bypass surgery: you want heparin because it starts acting fast and can be reversed quickly with protamine. you don't want the patient clotting on the machine, but you also don't want him/her bleeding when they come off bypass
 
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