Though I never rotated there, I visited the institution when I interviewed for EM residencies. The EM program in particular is very strong...the weak point is the city of Toledo itelf, blech!
Overall, it is a large hospital with DO medstudents and MD students from MCO.
Overall, I enjoyed being at this hospital. It's not huge, but is good sized and was always busy.
They have a strong partnership with the Medical College of Ohio (my school), and as such, MCO students rotate through IM, Surg, and Peds. Also, I'm not sure what the exact arrangement is, but residents go back and forth between MCO hospital and St V's. All the residents I worked with in Peds and Med/Peds were really great.
Unfortunately, there is strong competition in Toledo between St. V's/Mercy Health and Toledo Hospital/ProMedica. Specifically in Peds, this reduces the volume of patients.
What field were you looking at?
Also, as has been said, the major downside is Toledo itself. It's a smaller, very blue-collar town. I feel sometimes we're living about 5 years behind the curve in terms of culture/technology/trends. Just one example, broadband internet access has just in the last year or so become widely available here.