Feb 8, 2016
19
1
Hello
I was reading this in Kaplan Biochemistry Lecture Notes but I tried to understand it and I could not. I really feel so frustrated. It does not make any sense to me
I share quarter of my genes with my grandfather and my cousin share quarter of his genes with my grandfather too.How come I do not share quarter of my genes with my cousin?
Can anyone explain?
thanks
 
Last edited:

DrPicard

2+ Year Member
Sep 22, 2015
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I vaguely remember understanding this as follows:

With your parents you share 1/2 your genes.
With your siblings you share 1/2 your genes on average.

So with first degree relatives you share 1/2 your genes.

For every additional degree of relation, multiply by 1/2.

So for your grandfather, 1/2 x 1/2 = 1/4.
Uncle = 1/2 x 1/2 = 1/4.
First cousin = 1/2 x 1/2 x 12 = 1/8.
 
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OP
D
Feb 8, 2016
19
1
I vaguely remember understanding this as follows:

With your parents you share 1/2 your genes.
With your siblings you share 1/2 your genes on average.

So with first degree relatives you share 1/2 your genes.

For every additional degree of relation, multiply by 1/2.

So for your grandfather, 1/2 x 1/2 = 1/4.
Uncle = 1/2 x 1/2 = 1/4.
First cousin = 1/2 x 1/2 x 12 = 1/8.
Hey
thanks I understood the rule but I do not know why it is like this
maybe I will memorise the rule if no one replies
 

DrPicard

2+ Year Member
Sep 22, 2015
146
66
Status
Medical Student
You get 1/2 your genes from your mother.

Your mother gets 1/2 her genes from her father, half from her mother.

This means that of the 1/2 genes you got from your mother, 1/4 came from your grandfather, 1/4 from your grandmother.

(this is a simplified explanation but its basically probability math)
 

mw18

5+ Year Member
Jan 7, 2014
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Hey
thanks I understood the rule but I do not know why it is like this
maybe I will memorise the rule if no one replies
Is your question why brothers and sisters are half genetically? Because that is what I think you're missing. Your mom and your grandfather share half of their DNA (because it came from him directly). Your uncle and your grandfather share half of their DNA (because it came from the grandfather directly). Your uncle and your mom share half their DNA (from their mom and dad), but it's not the same half of the DNA that they share with their father. It's a different combination. Which is why your cousin wouldn't have the same quarter of the DNA you have. Because they got half of a different combination.
 
OP
D
Feb 8, 2016
19
1
You get 1/2 your genes from your mother.

Your mother gets 1/2 her genes from her father, half from her mother.

This means that of the 1/2 genes you got from your mother, 1/4 came from your grandfather, 1/4 from your grandmother.

(this is a simplified explanation but its basically probability math)
Is your question why brothers and sisters are half genetically? Because that is what I think you're missing. Your mom and your grandfather share half of their DNA (because it came from him directly). Your uncle and your grandfather share half of their DNA (because it came from the grandfather directly). Your uncle and your mom share half their DNA (from their mom and dad), but it's not the same half of the DNA that they share with their father. It's a different combination. Which is why your cousin wouldn't have the same quarter of the DNA you have. Because they got half of a different combination.
So what I understood is that I get quarter of my genes from my grandfather so does my cousin but we do not necessarily share the same quarter.
Thanks now it makes more sense