BOTH How to modify bioavailability of drug?

[myvow]

i i think acidic medium =stomach, so drug interaction can be applied in this case?using some drug to alter the motility rate of gastric emptying?

ii I think the drug is OK because extraction ratio is not too high,but I have no idea to explain in detail

iii it must change the rote of administration because the drug will be digested by gastric acid.


can anyone give me an advice if my answer is valid?
Thank you very much

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