SDN Members don't see this ad. (About Ads) Why do genetic mutations seem to proliferate with relative ease when inbreeding is concerned? I understand that the gene pool would essentially only contain a limited number of genes as a result of both breeders having the same gene pool, however, I don't understand what exactly enhances the chances of a genetic mistake to occur. I'm not looking for a detailed account of the mutation process, just something short, sweet and to the point. Thanks, guys.