There are two ways of looking at this issue. The easy way - and the more challenging way. What is important - in this stats obsessed world - is that you get all "A" grades. Sadly, it should be how willing you are to challenge yourself, or how much you learn. (But we know this is not really the case) If you like chemistry - place out of intro, and take gen chem w/lab then take (pchem w/lab, or inorganic w/lab, or quant w/lab). If you don't really like chemistry, or lack the confidence that you will get "A"s in the post-gen chem classes, take intro w/lab and gen w/lab. I did neither, and am suffering un-needed anxiety since Pchem had no lab, and am worrying that my honors project (in metallo-organic complexation chemistry) will serve this deficit - I got a "C" in pchem - which I worked hard for since I didn't know how to do partial derivatives when the class started- at the detriment to other class grades. Now, it looks like it all will work out, but be smart about it - take intro and gen w/lab and be done. Unless you think you can show off with "A"s in one of the other courses...... It's your call.