Will this be worth it is more a subjective question. The debt to income ratio is going to be very high, I expect you to owe something on the order of 300% of your take-home income when you're done, so that basically is a house mortgage before a house mortgage. Depending on the public service forgiveness is a gamble as is going into uniform right now.
You can expect a lower middle-class lifestyle for the first decade as not only are you paying off loans, you will be getting your practice started (or being an employee). That is no better or worse than physicians and others (I exclude dentists as they have a much higher burden than the rest of us). Your salary is much lower though, and as such, your expectations for the good life have to match what you get out of being a vet, both on the pecuniary and nonpecuniary side. If you do not want to do small-animal vet work, that is not easy at all.
Debt management is actually not as easy as people make it out to be, because you're talking with people in survivors bias, we made it work. The way I usually test my own staff on the matter is to not draw a salary for three paychecks (put it completely into a 401k), and then ask how that worked out for them. If they can manage that, then they'll usually be fine. Otherwise, you have to evaluate your expectations otherwise. Health care providers of all stripes complain about the debt to income ratio, and you may be no different.
Penn is on the more expensive side, and you're going to have to re-evaluate your values. You will not be financially independent, you will be forced to work, and you will probably have to work under non-ideal circumstances because everyone else has figured out that you have debt and will negotiate accordingly. If you say that every decision you've made has been toward vet, then this is manageable. But, you cannot have all of those values simultaneously, you are going to have to give something up. Will those values be worth it if you get to practice as a vet, that is an answer you can only answer for yourself. Are the opportunity costs high with the debt you incur, yes, because you will not be independent for at least a decade afterwards, you will have to work to come back to even. But, you get the practice and being a vet. Hope that will be good enough, because that is what you will have.
I can say in
@MusicDOc124 's case that the thought of the value proposition has crossed his/her mind as it has for me. There are certainly days when you regret it (especially with a child where you wish you could give more), but for us, there are more days we exult in the fact that we have what we do. And in my case, where I am free from any other involuntary obligations, I reflect that I would have been financially better off to not go into my profession, but I have a good time in it that I'm not particularly regretful of the lost opportunities. It's a mixed blessing, but I feel that I'm on the winning side of that trade, but I know of many people who feel trapped and the opposite. Without work as a comfort, it becomes a hell.