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Just wondering yalls thoughts / practice. I've had a few anasarcic obese chf exacerbations that appear to comfortably diurese 10-15 L/d (stable lytes, bicarb, renal fxn, vitals). My staff in these instances has had us back off of diuresis. Obviously the data points we follow to evaluate efficacy of and complications from diuresis aren't perfect indicators of fluid / lytes / etc shifts, but I haven't seen instances of harm coming from vigorous diuresis in absence of changes in those indicators. Have you all seen bad outcomes from I've diuresis in these situations / do you limit your rate of diuresis?