I've been going back and forth between PhD and MD/PhD programs for a while. I'm currently a SURP student at Sloan Kettering, and being here is really making me consider MD/PhD again. I was really unmotivated my freshman year because I didn't know what I wanted to do and was taking classes I didn't like, so I ended up with a 3.1 GPA (B's in some psych classes, C in organic chem I). I'm a Biochem major, and since then my semester GPAs have been 3.79, 3.86, 3.57, and 3.866. My cumulative GPA is now a 3.58, and I know I'll be able to bring it up higher by the end of senior year. I have been doing research since the spring of my sophomore year. I did one summer of full time research at my college (small liberal arts) and I am currently a SURP student at Sloan Kettering. I will have attended 2 national conferences by the time I graduate. I haven't taken the MCAT yet because up until now I was just considering PhD, so if I do decide to go this route I will be taking 2 year off to work as a lab tech somewhere in NYC so I can take the MCAT and get some shadowing experience. Do you think PD/PhD programs (Tri-Institutional being my top choice) are out of reach because of my freshman year GPA?