Do you want to be a little bit more specific? What are you concerned about? What is your spouse concerned about? Without telling anyone's life story spouses either work or have babies. A gross oversimplification.
Our class has 6 married people and about another 5-6 living with the significant other. All that I am aware of, husband or wife works or stays home with kids. If you have kids you get WIC, Food Stamps and medicaid and take out extra money.
I only have one semester of school under my belt, but it went pretty well. The best advice is for your spouse to find something to do (work, volunteer, etc.) or he/she will go insane. I was lucky my wife started her first teaching position in August so she has been just as busy as me. Although she doesn't make much, it's enough to help with our expenses and limit the amount of loans I took out this year. Finally, live on a budget! It will help prevent you from spending too much, and get the most out of your loans.