I’ve posted this in couple of other threads, and I don’t want to get too repetitive, but >200,000 in debt (not even including interest) is life-altering. Yes you will almost certainly be able to pay it back, but you’ll need to plan your entire life around it for 5-10 years, if not more. That debt will be on your mind when you have children, when you buy a house, when you start saving for retirement, etc. In my opinion, if it’s avoidable, it’s just not worth it. Furthermore, I can’t imagine that having the Geffen scholarship on your resume would limit your residency options in any way. UCLA has a national reputation and I’m confident with good board scores, you could go anywhere.
I have a good friend who went to school in SoCal and the atmosphere there is incredible- great weather, beautiful scenery, generally more laid back people. The only downside is the cost of living, but on the Geffen, that’s no concern for you! UCLA has pretty robust research offerings in the life sciences given that it’s an Amgen site, and those are only at institutions with strong research programs. I don’t think you could go wrong with UCLA. Congratulations!