John D. Loeser, M.D.
John D. Loeser is one of the deans of pain medicine, with a long history of involvement in the field, with many contributions that helped shape the specialty. He received his B.A. from Harvard University, his M.D. at the New York Medical School (NYU) in 1961, a surgical internship at UCSF, and completed his 5 year neurosurgical residency at the University of Washington. He served as a surgeon in the military, and was an Assistant Professor at the University of California, Irvine. Dr. Loeser is recognized as an expert in the surgical treatment of pain and multidisciplinary pain management. He was the Director of the Multidisciplinary Pain Center from 1982-1997. The University of Washington granted Drs. Loeser and Fordyce an independent yet multidisciplinary hospital ward for inpatient and outpatient pain management in 1983. The resulting Multidisciplinary Pain Center (MPC) implemented the biopsychosocial model of pain management that displaced the traditional biomedical model in the 1970s in Washington State [and Dr. Loeser believed nationally].
In the MPC, chronic pain was viewed as “a psychological and environmental disorder that is rarely amenable to biologically based ‘fixing’, especially by the time of referral”. He believed because pain could not be measured objectively, that we are relegated to treating pain behaviors instead of pain itself, since the VAS and other reported pain measurements are entirely self reported subjective measurements. The typical chronic pain patient treated at MPC came with diagnoses that did not explain their protracted pain, long beyond the usual time required for healing. According to Dr. Loeser, these patients were “like a billiard ball caroming off one cushion to another cushion, as each physician referred them to another physician. He believed finding a “cure” or reducing subjective pain is not as important as symptom relief and functional improvement. The MPC focused on reducing self-reported pain, improving psychological well-being and physical condition, and managing opioid use appropriately. The MPC required patients taking multiple opioids from different prescribers to relent that the medications were not solving the problem, as they all complained of pain and disability despite their heavy opioid use. A “pain cocktail” tapering strategy was used, and patients were informed they would be off opioids by the 21st day. However, in a 2014 American Pain Society lecture he admitted that none of these patients at the MPC were on the megadoses of opioids seen being used in 2014, and he has doubts the opioid strategy they used at the MPC would work for todays patients. Nonetheless he concludes “multidisciplinary pain clinics remain the best available treatment for appropriately selected pain patients and the lessons learned at the MPC could be translated into an individual practitioner’s methods of managing chronic pain patients”. He also noted in another lecture that the use of multidisciplinary pain clinics had peaked due to the high cost of rendering care in this model.
His career also focused upon pediatric neurosurgery. His research and teaching efforts have included the development of the human nervous system, neuropathic pain, low back pain and multidisciplinary pain management. His contributions to the field of pain medicine included laying the groundwork for pain fellowships, establishing the multidisciplinary approach to pain, and synthesis of taxonomy of pain. Dr. Loeser is connected with virtually all facets of the modern pain organizations and has spent much of his professional career at the University of Washington where he held professorships in both the Department of Neurosurgery and the Department of Anesthesiology, and served as director of their multidisciplinary pain clinic from 1982-1997 and since 2008 has been Professor Emeritus, yet is still very active in the pain world. In 2012 in an IASP Update, he discussed “Five Crises in Pain Management” that included (1) the lack of evidence for the outcomes of most of the things providers do for patients, (2) the inadequate education of primary care providers about pain and how to treat it, (3) the largely unknown value of opioid treatment for patients with chronic nonmalignant pain, (4) funding for the providers of pain management, and (5) access to multidisciplinary care.
A 2017 address by Dr. Loeser entitled “Illuminating the Path to Multidisciplinary Pain Management” for the APS distills his philosophies of pain medicine:
“Pain professionals face a real challenge of acquiring new knowledge and applying that to patient care. But we also have to make use of the knowledge that is already available today and organize that into effective patient care strategies. For chronic pain patients we need to recognize the increasing evidence that it is not due to a broken part that can be fixed, but is the result of central processing of information that is not only acquired through nociceptors, but also through afferent and environmental factors. We know that for example, anticipated consequences and past experiences can strongly influence the perpetuation of chronic pain. Chronic pain is a brain disease, and we can not only modify the disease by drugs or surgery, but also by psychological techniques and making use of environmental contingencies. Multidisciplinary pain management utilizes all these principles and thus far has been the best treatment for chronic pain patients that is available today. Chronic pain is a disease of the brain, and there are tools to manipulate the brain and reduce the amount of pain and suffering that a patient has, beyond and above injections and drugs. Cognitive and behavioral strategies have been proven to be effective in the management of chronic pain patients.”
Since 2007, the University of Washington has held an annual John D. Loeser Pain Conference. He continues to be active as a warrior in the world of chronic pain.
His publications include over 150 articles of original research, another 90 review articles, 128 book chapters, and is editor or author of eight books. His early 1970s publications were pediatric neurosurgical, but beginning in 1979 began a series of seminal pain management publications including Dorsal column and peripheral nerve stimulation for relief of cancer pain (1979), Role of neurosurgery in visceral and perineal pain (1979), Nonpharmacologic approaches to pain relief (1980), Low back pain (1980), Deafferentation and neuronal injury (1980), Brain stimulators for pain (1980), Orthopaedic aspects of the chronic pain syndrome (1980), Neural mechanisms in pain and analgesia (1981), Dorsal Rhizotomy (1982), Chronic pain (1983), Tic douloureaux (1984), Unlocking the secrets of pain. The treatment: a new era (1987), Disability, pain and suffering (1989), Selection of patients for neurosurgical procedures for relief of pain (1989), Inpatient pain treatment program (1989), Peripheral nerve disorders (1990), Pain after amputation: Phantom limb and stump pain (1990), Pain of neurologic origin in the hips and lower extremities (1990), Neurosurgical operations involving peripheral nerves (1990), Pain relief and analgesia (1990), Desirable characteristics for pain management facilities (1990), The role of pain clinics in managing chronic back pain (1991), Epidemiology of low back pain (1991), Neurological procedures for cancer pain (1992), The International Association for the Study of Pain: History and Philosophy (1995), Mitigating the Dangers of Pursuing Cure In: Pain Treatment at a Crossroads (1996), President’s Address to the 8th World Congress on Pain (1997), Basic Consideration of Pain: History of Pain Concepts and Therapies (2000), Generalized Pain Syndromes (2000), Regional Pains: Abdominal Pain Caused by Other Diseases (2000), Master the AMA Guides 5th Ed., A Medical and Legal Transition to the Guides to the Evaluation of Permanent Impairment (2002), Taxonomy and epidemiology of spinal cord injury pain (2002), The Role of the Multidisciplinary Pain Clinic (2002), Opiophobia and Opiophilia (2004), Multidisciplinary Pain Management (2004), Summary: From Biology to Narrative (2004), Surgical Pain Management (2005), Pain, Suffering and the Brain: A Narrative of Meanings (2005), Back Pain in the Workplace – the International Association for the Study of Pain’s Taskforce Report (2006), Pain as a Disease (2006), American Academy of Pain Management (Eds): Chronic Pain Management: Guidelines for Multidisciplinary Program Development (2007), Socioeconomic Factors in Pain and its Management (2009), A History of the Intersection of Business with Pain Medicine, in: The Devolution of the “Profession of Pain Medicine to the ‘Business’ of Pain Medicine” (2010), Taxonomy of Pain Systems, in: Comprehensive Pain Medicine and Interventional Pain Management Board Review (2011), Effects of Workers' Compensation Systems on Recovery from Disabling Injuries (2012), Radiofrequency gangliolysis of the trigeminal nerve for trigeminal neuralgia (2014), Pain Taxonomy (2015), Assessment of Chronic Pain: Domains, Methods, and Mechanisms (2016).