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Alright so anything that results in muscle damage can lead to myoglobinuria, so one of the hallmarks for McArdle dz is myoglobinuria since accumulation of glycogen in muscle can damage the muscles.
Then how do you explain the myoglobinuria in carnitine deficiency? First Aid doesn't mention about myoglobinuria, but Kaplan biochemistry does.
I am assuming the accumulation of fatty acids in muscle may lead to myoglobinuira I guess?
If so, can anyone explain how the accumulation of glycogen or fatty acids can damage muscle?
Many thanks in advance.
Then how do you explain the myoglobinuria in carnitine deficiency? First Aid doesn't mention about myoglobinuria, but Kaplan biochemistry does.
I am assuming the accumulation of fatty acids in muscle may lead to myoglobinuira I guess?
If so, can anyone explain how the accumulation of glycogen or fatty acids can damage muscle?
Many thanks in advance.