New Case Posted - Docetaxel Induced Canalicular stenosis by Jordan Graff, MD

[Andrew_Doan]

http://www.eyerounds.org/case31.htm

Please use this thread to discuss and present questions to the forum members.

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[retinadoc]

I wonder if topical steroids could have prevented the stenosis. Do you know if this has been tried?

 

[Andrew_Doan]

I wonder if topical steroids could have prevented the stenosis. Do you know if this has been tried?

Even on topical steroids, stenosis occurred:
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=12879466

There is one case study encouraging the use of topical steroids:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8549238

There aren't any good randomized clinical studies, however.