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MCAT: Medical College Admissions Test
MCAT Study Question Q&A
On a molecular level, why does exercise/shivering->heat?
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<blockquote data-quote="Professional Student" data-source="post: 19015619" data-attributes="member: 788957"><p>To think that the heat produced by shivering is due to friction is frankly, pretty silly. The heat is produced by the inefficiency of ANY energy transformation. When ATP is converted to ADP in order for the myosin-actin filament interaction to occur, the MAJORITY of the energy released is lost directly as heat. There is no energy transformation reaction that exists in the world that is more than 30%-40% efficient. The remaining 60%-70% is lost as heat energy. This result is exemplified again in the presence of a fever when the body is fighting infection. A vast amount of energy (ATP) is being used by the body to restore homeostasis, resulting in raised body temperature even though there is no shivering. The heat produced from shivering is also from the ATP being inefficiently consumed by the body, just like during a fever, but this time the reaction is the harmless contraction of muscle fibers and not the inflammatory response of the immune system. </p><p></p><p>To say that the heat is a result of friction of the sliding filaments is adding an unnecessary step to think about. I'm sure some heat is produced by friction, but the fraction is insignificant compared to the energy lost during the hydrolysis of ATP. You will learn that every chemical reaction is inefficient, but biochemical reactions are especially inefficient. If the filaments were producing that much heat from friction they would quickly degrade from the mechanical stress, similar to wearing a hole through the threads of cloth.</p></blockquote><p></p>
[QUOTE="Professional Student, post: 19015619, member: 788957"] To think that the heat produced by shivering is due to friction is frankly, pretty silly. The heat is produced by the inefficiency of ANY energy transformation. When ATP is converted to ADP in order for the myosin-actin filament interaction to occur, the MAJORITY of the energy released is lost directly as heat. There is no energy transformation reaction that exists in the world that is more than 30%-40% efficient. The remaining 60%-70% is lost as heat energy. This result is exemplified again in the presence of a fever when the body is fighting infection. A vast amount of energy (ATP) is being used by the body to restore homeostasis, resulting in raised body temperature even though there is no shivering. The heat produced from shivering is also from the ATP being inefficiently consumed by the body, just like during a fever, but this time the reaction is the harmless contraction of muscle fibers and not the inflammatory response of the immune system. To say that the heat is a result of friction of the sliding filaments is adding an unnecessary step to think about. I'm sure some heat is produced by friction, but the fraction is insignificant compared to the energy lost during the hydrolysis of ATP. You will learn that every chemical reaction is inefficient, but biochemical reactions are especially inefficient. If the filaments were producing that much heat from friction they would quickly degrade from the mechanical stress, similar to wearing a hole through the threads of cloth. [/QUOTE]
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MCAT: Medical College Admissions Test
MCAT Study Question Q&A
On a molecular level, why does exercise/shivering->heat?
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