PPI for Barrett esophagus after esophagoduodenostomy?

[pzh200707]

During the EGD, Barrett esophagus is diagnosed. Omeprazole is taken following the surgery.
Without parietal cells, how does PPI work?(or some metaplastic cell have acid secreting function which can be suppressed by PPI?)

Would EGD increase the risk of bile reflux and aggravate metaplasia?....

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[zhopv10]

Not sure if there was more to the question but normally there would be parietal cells, the PPI would act on those and reduce acid and reduce the irritation to the esophagus.


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[Transposony]

Not sure what you are asking since esophagoduodenostomy is removal of entire stomach which is only done for Ca stomach.