question about AChE

[synapse]

what is the purpose of using acetylcholine esterase staining? why would you want to locate it?

---

Members don't see this ad.

 

[VPDcurt]

vesicle recycling, endocytosis, exocytosis i believe.

 

[KiKat37]

ACh is a neurotransmitter that carries "messages" between motor nerve cells and muscle cells. Acetylcholinesterase is an enzyme that destroys the excess ACh that is left in synapses after a "message" is transmitted. As far as I remember, acetylcholinesterase staining is used to identify peripheral (PNS) connections.

 

[Newquagmire]

might be useful to see if it's being sequestered somewhere such that it cant catalyze ACh degradation but would still appear present according to quantitative measures.