The problem is in trying to keep the comments related to grades alone as much as is possible. Based on this, yes, there are a number of schools where 4.0 GPAs are much easier to come by, and I would be equally or more impressed by a 3.7-3.8 from a top school than a 4.0 from a mediocre university with rampant grade inflation (notice I used the term non-selective, which should imply that I am not throwing out all schools outside of the top 30). With this said, I thought it was understood that applications are not viewed in a vacuum. Obviously MCAT scores, research/publications, and other factors come into play. Despite the strong language used (which you are correct to call out), I wouldn't auto reject a 4.0 with a high MCAT score and excellent recommendations/ECs based on institution alone. The transcript, however, would mean much less to me and more emphasis would be placed on other factors such as the MCAT.
Here is a somewhat extreme example of my definition of non-selective (this is real data from 2012):
School #1:
- Percent of Applicants Admitted: 84%
- Average High School GPA: 2.80
- Test Scores -- 25th / 75th Percentile
- SAT Critical Reading: 390 / 460
- SAT Math: 390 / 460
- SAT Writing: 370 / 450
- ACT Composite: 16 / 20
- ACT English: 14 / 19
- ACT Math: 15 / 18
School #2
- Percent of Applicants Admitted: 67%
- Average High School GPA: 2.75
- Test Scores -- 25th / 75th Percentile
- SAT Critical Reading: 400 / 470
- SAT Math: 400 / 470
- SAT Writing: 370 / 450
- ACT Composite: 17 / 19
- ACT English: - / -
- ACT Math: - / -
- A 3.0 GPA and a 1550 combined SAT score (out of a 2400 maximum) would qualify you for their "honors" college.
Obviously these are extreme examples, but they illustrate my point nicely. I would set the bar much higher. At the two institutions listed, the grades would be absolutely worthless to me if I was an adcom (assuming a curve is used and even in the absence of a curve, one would wonder how easy the curriculum would need to be to allow a portion of the class to even pass). The decision would hinge all on the MCAT/research/ECs, and even then, I would probably still have concerns about ability to balance a difficult course load (but I wouldn't auto reject an applicant because of this).