I can definately relate to your questions. I will be starting PA school next week so I am relatively familiar with the application process as I just completed it this last summer/fall. I definately agree with the other responses you have received. PA programs really seem to look at a number of factors when they consider an applicant. True, they want somebody who will be able to handle the course work, but also someone who has medical experience and is mature enough to handle the stresses that the health care profession brings with it. I can tell you a little bit about myself so you can have something to go by. I am 24 years old, have been an EMT for over 5 years(working full time the past two years), graduated this last May with a B.S. in biology, chem minor. I had a cumulative GPA of 3.3 and scored relatively well on the GRE, which many programs now require. I know that my GPA is not ideal and I can make excuses for that C in calculus like everyone else, but I really don't think it's necessary. I think that my case is fairly typical, at least in my class. I hope that helps.