Acute PE doesn't cause RV hypertrophy....your heart obviously doesn't hypertrophy that quickly. RV hypertrophy can occur with chronic thromboemboli or any other form right sided pressure overload, i.e., the full differential of pulmonary HTN.
EKG changes in PE are due to Acute RV dilation and strain, not the hypertrophy....and the classic S1Q3T3 is not specific to PE, it can occur with any cause of Acute Cor Pulmonale.
EKG changes that I look for...
1. Sinus tachycardia, easily forgotten
2. S1Q3T3-5% at best
3. New IVCD (with RBBB morphology) or Complete RBBB
4. Deep S waves in I/AVL with Q waves III (sparing other inferior leads)
5. Low voltage
6. TWI V1-V4/III/AVF-"RV strain"
7. Late R/S transition