I'm a 4th year at Wayne State, so here's my take on some of the +/-:
Positives:
-Large class size means that you will almost certainly find a place to fit in.
-Lots of different activities (we are rumored to have the most different student groups of any med school)
-Excellent clinical training - we are the ONLY school in Detroit, which means that 1. we go to ALL of the teaching hospitals around here and 2. we don't have to share pathology.
-WSU grads are well respected (also true of the other schools you're looking at), especially in the Midwest. I'm applying in OB and every program says that they love Wayne grads.
-Cheaper than the other schools.
-Administration who does listen (although not always act) to us. I can see improvements from my class to the MS1 class in terms of course arrangements, many of those changes were suggested by students.
Neutral aspects (ie some may like this, some may not):
-1st 2 years are traditional lecture style, but they are trying to increase the clinical relevance (ie, in 1st year there is an Intro to the Patient course)
-BIG class size.
Negatives:
-Metro Detroit. I hate it. (but to be fair, others love it) But I'm also from a small town and I dislike big cities in general.
-Constantly switching hospitals in the clinical years. I think I've been to 10 different ones, which means relearning things like where are the bathrooms, what forms are unique, etc.
Hope this helps.
Kristi