schlieren

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Oct 31, 2009
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Berkeley Review Biology Section V, Passage IX, Q. 58:
"An infant with severe EF has jaundice, a yellow coloring due to excess bilirubin, a breakdown product of heme. In what tissue or orgam is heme degraded into bilirubin?
A. Spleen
B. Bone marrow
C. Liver
D. All of the above
"
Answer is D. Explanation says "All three of these organs produce bilirubin, a break-down product of heme."

However, Berkeley Review Biology Section VII, Passage V, Q. 24:
"The breakdown of heme to bilirubin takes place in the:
A. liver
B. spleen
C. pancreas
D. gall bladder
"
Answer is B. Explanation says "If we know where the human red blood cell is degraded, we know where the breakdown of heme occurs ... Old cells are removed from the circulatory system and degraded in the spleen."

Who is correct? Does heme breakdown in liver?

Previous questions: Q.1
 

RogueUnicorn

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Jul 15, 2009
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Kupffer cells in the liver break down heme, but the major organ is the spleen