I may be a crazy person, or I may just not know how to do statistical analysis. Both are strong possibilities. I just found something I didn't really expect when I ran on a meta-regression and I was wondering if anyone could bring me some clarity on this finding. Namely, that the size of the treatment effect was positively correlated with the severity of depression as measured by BDI. Far as I know, most treatments (SSRIs I know for sure) show smaller treatment effects the higher the BDI score is. (i.e. the more depressed you are the worse they work) If it turns out I'm not crazy, I'm kind of excited. Although that means a hell of a lot more work before this paper is ready.