Ajmeru

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Hi,
Just curious, does anybody know about the discovery of the Sonic Hedgehog gene (SHH) and how did it came to be known by this name? I couldn't find much in the literature on the web or elsewhere.
 

kidmel45

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actually had a prof in undergrad tell us it was named after the sonic the hedgehog sega game....not sure if that's true, but sounds better than anything else I've heard
 

Centrum

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Originally posted by kidmel45
actually had a prof in undergrad tell us it was named after the sonic the hedgehog sega game....not sure if that's true, but sounds better than anything else I've heard
I don't know of anything else called by the name sonic the hedgehog, so that would be my guess.
 
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Badgerbabe

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Yeah, my devo prof told us the other day that it is involved in patterning during development, and was in fact named for the sega game. Not sure why though.

Shannon
 

DrMom

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Originally posted by Badgerbabe
was in fact named for the sega game. Not sure why though.

Shannon
Maybe because molecular biologists are strange? ;)
 

Badgerbabe

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Oh, I'm quite certain molecular biologists are strange! (I can say this having been one in undergrad :) ) I would actually really like to hear the story behind that one....Well, we were up really late one night playing video games and one thing led to another, and someone lost a bet, and his next great discovery was named Sonic Hedghog.....?? :D
 

Fenrezz

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I don't blame them for naming it after the game. I was so addicted to that game I would have named my kid Sonic, had I had one.
 

DW

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Originally posted by Fenrezz
I don't blame them for naming it after the game. I was so addicted to that game I would have named my kid Sonic, had I had one.
well, i guess thats a better name than "Grand Theft Auto 3" or "Goldeneye" :)
 
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well since grad students name a lot of the genes - they have pretty funny names. the patchway for dorsal-ventral specification in drosophila embryos has gene names like cappacino, pipsqueak, toll, cactus, spatzle, lunatic fringe (some death metal band - not in this pathway but still amusing). makes learning them a bit more interesting. there are all sorts of variations on sonic hedgehog that hae sprung up too. yeah dorks! ;)

-jot
 

kutastha

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Just by memory, I believe there was already a hedgehog gene found in fruit flies, and the Harvard researchers who discovered the SHH gene had a sense of humor.
 

Coalboy

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I like how one of the genes that controls the development of the head is called noggin . Makes it pretty easy to remember. And my embryo professor told us a similar story to the one Kutastha related.
 

DrMom

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Originally posted by Fenrezz
I don't blame them for naming it after the game. I was so addicted to that game I would have named my kid Sonic, had I had one.
Scary thought all together, Fenrezz! ;) :laugh:
 
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