McNinja is correct. just because someone doesn't think an area is their cup of tea shouldn't be a reason for you to stay away.
I'll reiterate my point about visiting before you make your decision though.
The positives of the RGV are that there is great fishing, bird watching, south padre island can be really nice not in tourist season when there is trash everywhere on the beaches and overzealous partiers, some of the best mexican food I've ever eaten, some shopping/retail in McAllen and zoo in brownsville is good. the overall crime rate published is not bad when compared to say san antonio or houston. Traffic is pretty good especially if you are moving from a big city. McAllen is a fast growing area. Overall the area has a very low cost of living. theres lots of EM jobs paying huge money there.
Consider living in Rancho Viejo, Harlingen, north McAllen/sharyland or Mission. I would stay away from east McAllen/Alamo, and most of Brownsville. You can live on South padre if you can afford it but its not fun during tourist season. highly consider sending your kids to private schools.
the RGV is kind of like its own universe though, like I was saying it might be a culture shock. not bad/good, just different. if you want more information from someone who grew up there, feel free to PM me, I don't live there currently, or practice there for what it's worth so I can't give any job specifics.