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I was wondering if anyone in this forum has subspecialized in trigeminal neuralgias or neuropathic pain research.
I am very interested in pain research primarily from a clinical perspective as I am a dentist and secondarily because of the many pain research projects I have been involved with over the years. Although I don't work in the research milieu any longer, I am fascinated by pain research for my own intellectual curiousity.
As a graduate student, I had the opportunity to work on a pilot study involving "chronic constriction injuries" (CCI) of the sciatic nerves in rats , which is an internationally recognized neuropathic pain model developed by the professor I was working with. The landmark study on CCI is the following: Bennett, G.J. and Xie, Y.-K.: "A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man". Pain 33: 87-107, 1988
http://www.hosppract.com/issues/1998/10/bennett.htm
I also had the chance to work on some neuro based research with another professor which was related to the trigeminal thalamo-cortical somatosensory pathway and tried to relate it to the infamous studies done by Pons et al. , "Massive Cortical Reorganization After Sensory Deafferentation in Adult Macaques". Science, Vol. 252, 1991, pp. 1857-1860a. This landmark study hinted at possible neuroplasticity occuring in macaque monkeys that had sustained some deafferentation of many cervical nerves and exhibited neuropathic pain not unlike "phantom limb pain".
http://apu.sfn.org/content/Membership1/MemberObituaries/ObituariesArchive/pons.htm
Anyone on this forum involved with research pertaining to pain conditions restricted to the head & neck region?
Comments?
I am very interested in pain research primarily from a clinical perspective as I am a dentist and secondarily because of the many pain research projects I have been involved with over the years. Although I don't work in the research milieu any longer, I am fascinated by pain research for my own intellectual curiousity.
As a graduate student, I had the opportunity to work on a pilot study involving "chronic constriction injuries" (CCI) of the sciatic nerves in rats , which is an internationally recognized neuropathic pain model developed by the professor I was working with. The landmark study on CCI is the following: Bennett, G.J. and Xie, Y.-K.: "A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man". Pain 33: 87-107, 1988
http://www.hosppract.com/issues/1998/10/bennett.htm
I also had the chance to work on some neuro based research with another professor which was related to the trigeminal thalamo-cortical somatosensory pathway and tried to relate it to the infamous studies done by Pons et al. , "Massive Cortical Reorganization After Sensory Deafferentation in Adult Macaques". Science, Vol. 252, 1991, pp. 1857-1860a. This landmark study hinted at possible neuroplasticity occuring in macaque monkeys that had sustained some deafferentation of many cervical nerves and exhibited neuropathic pain not unlike "phantom limb pain".
http://apu.sfn.org/content/Membership1/MemberObituaries/ObituariesArchive/pons.htm
Anyone on this forum involved with research pertaining to pain conditions restricted to the head & neck region?
Comments?