IkramKhaliq
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This might be a really stupid question (forgive me )
If we were to administer the MMR vaccine to a patient, what would the best effector cells be?
a) B cells
b) CD8 cells
c) CD4 cells
Given that the vaccine is a live attenuated virus, I assumed (correctly) that the best effector cells would be CD8 cells. But then I got confused. Since viral antigens are presented on MHC-I and would logically activate only CD8 T-cells, how do we get an antibody response to the MMR vaccine? I'm assuming we do because we measure IgG for proof of vaccination. What activates the helper T cells to allow class-switching?
If we were to administer the MMR vaccine to a patient, what would the best effector cells be?
a) B cells
b) CD8 cells
c) CD4 cells
Given that the vaccine is a live attenuated virus, I assumed (correctly) that the best effector cells would be CD8 cells. But then I got confused. Since viral antigens are presented on MHC-I and would logically activate only CD8 T-cells, how do we get an antibody response to the MMR vaccine? I'm assuming we do because we measure IgG for proof of vaccination. What activates the helper T cells to allow class-switching?