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Hi all, I'm new to this forum and in the middle of study for Step 1. Took the form 1 on friday and am going over my answers...I found a bit of a contradiction in a question regarding hereditary angioedema.
The question (paraphrased to protect copyright ): Young girl with an acute onset of facial swelling and dyspnea. Hereditary Angioedema is suspected (C1 esterase inhibitor), what will be found in serum?
1. Decreased serum C4
2. Increased serum properdin
3. Normal C1q
4. Normal C1s
5. Normal C2
In a bit of research I found out that:
So here...answers 1 and 3 could be true? I could be totally off but does anyone have an answer?
The question (paraphrased to protect copyright ): Young girl with an acute onset of facial swelling and dyspnea. Hereditary Angioedema is suspected (C1 esterase inhibitor), what will be found in serum?
1. Decreased serum C4
2. Increased serum properdin
3. Normal C1q
4. Normal C1s
5. Normal C2
In a bit of research I found out that:
Lab Studies:
* Routine laboratory tests are usually normal, although a leukocytosis may occur with gastrointestinal episodes. Elevation of the hematocrit may be observed because of intravascular fluid loss.
* Type I HAE
o C1-INH level is low.
o C4 and C2 levels are low.
o C1q level is normal.
* Type II HAE
o C1-INH level is normal or elevated but dysfunctional.
o C4 and C2 levels are low.
o C1q level is normal.
* Type III HAE
o C1-INH level is normal.
o C1-INH functional assay is normal.
o C4 level may be normal.
So here...answers 1 and 3 could be true? I could be totally off but does anyone have an answer?