I took naplex this afternoon!
I generally just lurk here, but I figured I'd post some info so perhaps someone could benefit from my experience. Everyone's been pretty awesome about giving their insight, so I figure if anyone can benefit from my insight, so much the better.
Overall, it's like what pretty much everyone has said--it's a lot of drugs, a lot of doses, and lots of name brands. For my preparation I pretty much used Prontopass and also the APHA book. Going in I felt like I knew the top 200 brands pretty well, although I wasn't comfortable with all the doses, dosage forms, etc.
I had about 10 math questions. They were all pretty simple: NaCl equivalent, ratio, percentages (I think about 3 percent questions at least) and some kinetics. There were 2 questions where you had to figure out the half life. There was one question where you had to figure out the loading dose, and one question where you had to figure out what rate to give the drug considering the desired concentration, Vd, etc.
I didn't really have too many diagnosis type questions like some of the other posters had. A few times I had to pick which disease state the drug was for, so you'd have to look at the patient's profile, look at the "diagnosis" part, and then figure out which diagnosis the drug was for.
I had 1 stats question, and also one question regarding the phases in drug testing/research.
For compounding, I think I had about 3 questions. I also had a few questions regarding sterility of products/autoclaving/dry heat/etc.
I didn't have many OTC type questions.
There was quite a bit on asthma, HTN, heart disease.
Oh, and I swear there were about 5 questions about olanzapine. I have no idea why, probably because I didn't study that drug too much. But yeah, there were questions regarding the dosage, dosage form, etc.
The awful part about the exam is the computer adaptive part. I'd get a really easy question (what to tell a patient regarding NTG) and I'd be thinking, oh no, I must have gotten a LOT wrong to get a question that simple. But at the same time, I was elated to have a really simple question!
The best part: no HIV drugs, only one chemo question, no brutal kinetics (the kinetics that showed up was easy), and no crazy tricks. For the most part the question were pretty straightforward. With the math, just be sure to look at the answers and see if they are in grams or milligrams.
Oh, and the biggest WTF question had to do with support stockings. I was like, wait, isn't this a pharmacy exam????
Hopefully I passed! I'm hanging on to my Prontopass until I find out for sure...