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Yup, had an attending in residency do that too. The patient died within about 10 minutes of pushing it. Wrecked the guy for months afterwards.Same here, this one was not even that long ago. It was a transfer from an outside hospital and the doc pushed TPA right after the non contrasted CT Head and before the CTA only to find out they had a gigantic Type A dissection extending up the carotid. Needless to say, it did not end well for the pt.
I had a case in residency with a woman that had sudden onset severe headache. She had severe dysarthria, some expressive aphasia, decreased alertness, a R sided facial droop, although she had a history of a prior CVA but family didn’t come to the ER and EMS didn’t ask if she had a baseline deficits. She was still in severe pain in the ER. CT non con was negative. Neurology said to push tPA. I said I did not feel comfortable doing that and felt that she needed an LP to r/o SAH as the pre-test probability was so high that I could not rule it out with a CT non-con. The neurologist came down and pushed it himself even after my attending urged him not to. About 20 minutes after, I had to intubate the patient as she had become unresponsive and had vomited and aspirated. CT non-con now shows a clear SAH. She was palliatively extubated later that evening.
For the neurology residents and attendings reading this thread, this is why EM docs are frequently so cautious about possible ischemic stroke cases that are atypical. Sure, a benign stroke mimic is unlikely to have adverse outcomes to tPA, but there are numerous ischemic stroke mimics that will kill the patient if tPA is given. Specialists frequently get tunnel vision in acutely ill patients and have a tendency to anchor on diagnoses of their specialty (not saying we EM docs don’t anchor). We went to residency specifically to learn how to manage undifferentiated patients and were taught from day 1 about the importance of avoiding anchoring. We understand y’all’s expertise in strokes, but there is such a wide differential for the acutely altered patient that we are much more familiar with.