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TPR Q: increased level of testosterone in blood decreases the production of FSH?

Discussion in 'MCAT Study Question Q&A' started by premed08, May 17, 2008.

  1. premed08

    premed08 7+ Year Member

    Aug 19, 2007
    I was reading TPR biology and came across this question on pg.326. I dont understand why this would happen. I expected the opposite since testosterone stimulates spermatogenesis and FSH stimulates sertolli cells aid spermatogensis. So wouldn't it be high lebels of testosterone would lead higher levels of FSh in the blood?

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  3. BloodySurgeon

    BloodySurgeon Moderator Emeritus Lifetime Donor Classifieds Approved 10+ Year Member

    Nov 19, 2006
    hSDN Member
    hSDN Alumni
    Hypothalamus --> GnrH ---> Anterior Pituitary ----> LH --> Leydig cells ---> testosterone.

    To counter the effects of too much testosterone, testosterone does a negative feedback on the hypothalmus to inhibit GnrH which inhibits both LH and FSH.

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