Acute bacterial pneumonia normally presents with more toxicity. Significant fever, tachypnea and tachycardia. PE exam typically demonstrates purulent sputum. Course of disease is much quicker, typically under 5 days of illness before the patient presents. Dense lobar infiltrate on CT often with evidence of consolidation. Top 3 etiologic causes in the population are pneumococcus, h flu, and moraxella.
Atypical is much more insidious, often characterized as a walking pneumonia. Often afebrile, HR/RR normal, negative PE. Systemic symptoms are often stressed by the patient with a flu-like prodrome. Progression of disease is often 2+ weeks instead of days. Minimally to non-productive cough often with chest pain (from cough, not pleuritic) with negative sputum stain. CXR often negative or demonstrating typically unilateral interstitial infiltrate. Mycoplasma is the big one, chlamydia pneumoniae #2. Legionella is characterized as atypical but often has a more toxic presentation with systemic (particularly GI) involvement and more dense infiltrate on CXR, mostly seen in older male smokers. Mycoplasma and chlamydia are typically indistinguishable clinically and the diagnosis is made on clinical features alone.