Yeah, I agree, Irvine is not a haven for liberal artistic free expression--it is no Haight or Berkeley. But if you want to talk about the pros and cons of each location, the Sunset District, the home of UCSF, is one foggy place. Rather depressing, at times. (I did research there for a summer). And you can't beat the weather and beaches near UCI, unless you go to UCSD. Also, if you ever do get to go to LA, it actually has more museums than any other city in the U.S. (except for NY, of course). Only in LA do you get to see Beck play at an opening of his grandfather's post-humous show in a gallery in Santa Monica. The club scene in Hollywood can be really fun too. Also, LA has some really great pockets of diversity, just more spread out than in SF...there are whole "ethnic cities," not just "ethnic neighborhoods." I have to admit that I like both the bay area and southern cal almost equally. I do not know if I would necessarily choose UCI over UCSF--there are other factors than simply location at play for me. And since the application process isn't just based on numbers, I may not even get that choice.