I've been reading quite a bit of great advice in the SDN forums and even though my question seems to be a common one, I thought I'd just throw it out to see what ya'll think. First off, I didn't get accepted to med school this year. I'm not too surprised considering the sheer number of applicants this year, but I still am left wondering what I can do to improve my profile to show how serious I am about becoming a physician. As an applicant, my numbers are not too bad: 33S MCAT, 3.7 GPA with degrees in biology and chemistry. I have a total of five years of research experience with the past two years spent in the cancer research lab of a Nobel Prize winner where I was fortunate enough to be credited as a co-author on a paper published in the journal Cancer. My letters of rec were all from top-notch research professors, including the Nobel Prize winner. My volunteer experience is modest and my medical/clinical experience is quite light. Truthfully, the majority of my medical exposure comes from my wife of four years, who is nearing completion of her intern year as a pediatrician at OHSU. I applied to a number of schools, received secondaries from all of them, but did not recieve a single interview invitation. I'm already in the process of shadowing a physician and have started to volunteer in medical settings. While I know that these activites will help, I wonder if it will be enough. My question is: what else can I possibly do to increase my chances as a second-time applicant? Should I quit my current job to train as a CNA, get full-time volunteer experience, etc.? My current job isn't great (no research labs out here in Portland would pick me up when they found out I was applying to medical school and possibly available for only a year) but it pays a decent amount above minimum wage (with GREAT insurance) so I really would like to keep it if possible. Anyhoo, I'd really appreciate any advice. Thanks for your time.