I interviewed at Wayne State; it's a solid med school, I think if you're into emergency medicine, especially urban trauma, you're going to get the experience of a lifetime. WSU is the only med school in Detroit, and has monopoly over the hosptials. Plus, it's Detroit, you're gonna get trauma up the Yangtze. On the other hand, although Detroit is known for being run-down and dangerous, I felt it was just like any other big city. It's a big class at Wayne too though, 300+ students. However, I know some people prefer having a large number of peers, more variety of people to interact with. Also I think WSU is known for churning out excellent, well-experienced clinicians, whilst at the same time being very weak on the research side of things. So you might choose to go there if you have no interest in research and want a ton of gritty clinical experience.
UIC doesn't want to talk to me as of yet, so I can't speak for their school. UIC has slightly more prestige though, in terms of ranking.