no real formula for 250+, since people who have gotten that score do it in all different ways. best thing i did was spend time to flip thru the usmle step 1 experiences thread and jot down a few notes. i took a look at some of the sources i was thinking about and made sure that it would work for me. i didnt use goljan audio, kaplan set (except for kaplan biochem in the 7 volume set), but used similar sources and did fine. ive heard that your sources are good, but try to find someone who has used them before and find out if you think it would work for you. people have also written reviews of these sources in the experiences thread and you can get a sense of what they think and how they ended up scoring.