What exactly is the proximal cause of glossitis anyway?

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Ceteris Paribus

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I don't mean which conditions can precipitate it, but rather what is going on physiologically that the tongue is inflamed say in Iron deficient anemia, but not say the fingers and toes? This came up in class today and no one including the instructor could really give an adequate answer. I've looked in Harrison's and elsewhere where it is addressed in the context of other conditions, but nothing really gets to the point of the matter.
 
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