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Y Prolactin inhibits ovulation

Discussion in 'Medical Students - MD' started by Anthonyhopkins, Oct 31, 1999.

  1. Anthonyhopkins

    Anthonyhopkins New Member

    2
    0
    Oct 30, 1999
    New York
    Can anyone help me out in solving out the mystery, why prolacting increase inhibits menses in the females after pregnancy
     
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  3. avi newman

    avi newman Member 10+ Year Member

    60
    0
    Oct 29, 1999
    new york, new york
    my understanding of the relationship in general terms is that either a decrease in dopamine or a prolactinoma will increase the supply of prolactin...an increase in the supply of prolactin for whatever reason puts the brakes on GnRH production...and that's not good for ovulation...clinically, i know that when a mother breast feeds her baby the chances of her soon getting pregnant again go down...according to greenspan...the increase in the supply of prolactin inhibits the normal pulsatile secretion of LH and FSH...the production of these latter hormones depends upon a pulsatile as opposed to steady stimulation...i hope this is of some help...avi
     
  4. avi newman

    avi newman Member 10+ Year Member

    60
    0
    Oct 29, 1999
    new york, new york
    my understanding of the relationship in general terms is that either a decrease in dopamine or a prolactinoma will increase the supply of prolactin...an increase in the supply of prolactin for whatever reason puts the brakes on GnRH production...and that's not good for ovulation...clinically, i know that when a mother breast feeds her baby the chances of her soon getting pregnant again go down...according to greenspan...the increase in the supply of prolactin inhibits the normal pulsatile secretion of LH and FSH...the production of these latter hormones depends upon a pulsatile as opposed to steady stimulation...i hope this is of some help...avi

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    avi newman

     

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