PV loop question

Started by 5679utmed
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5679utmed

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Why in the case of increased or decreased isotropy, the pressure doesn't go higher or lower?

thank you
 

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  • CF025 PV loop-inotropy.png
    CF025 PV loop-inotropy.png
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Every point on the PV loop is a ratio between Pressure vs. Volume. y= Pressure and x= Volume. When you increase contraction, you shift the line left. Which means you get more volume pumped out for the same amount of pressure. (you get less End systolic Volumn = higher SV = higher EF, this is proof that it was pumped harder)

Compare that to increase in Afterload such as Aortic stenosis, you will get a taller PV loop, where you need higher Pressure to pump out the same amount of Volume @ the end of Isovolumic Contraction. (in contrast to the above, even though it looks like the y-axis is taller & higher Pressure, you get more ESV = lower SV = lower EF)

My point is a taller y-axis is not the only thing you should look for to check for an increase in Pressure.
 
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