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My fiancè who goes to a DO school has hypothyroidism and she struggles immensely with fatigue. I think if you have a newly discovered medical condition that affected your ability to score competitively on a high-stakes exam, you owe it to yourself to include it in your MSPE. Most PD's will ask you about the low score and likely look to your personal statement for some sort of explanation.
 
I'd mention it. Personally, if I saw an application like that with a rapid improvement in achievement and a diagnosis of a disorder like hypothyroidism that could easily account for it with initiation of treatment right about the time the improvement started, I'd all but disregard what happened before as not indicative of what the person can do now that they are stabilized.

Obviously that's just me and I'm not a PD, but I think it's obvious that for some percentage of programs that otherwise considered you borderline, this could easily be a game changer.

As was mentioned previously, you might want to talk to your dean and see if this can be included in your MSPE. They might say no (not sure why they would exactly), but if they include it, it might be a lower key and more "institutionally backed" acknowledgment of the reason for the shift in achievement.
 
@MrChance2 I shadowed an endocrinologist for a significant period of time and a number of her patients reported that receiving Synthroid treatment felt like a veil was being lifted from their mind.
 
Yeah, with me the big thing was the insidious onset. I had all the symptoms but its so slow you don't really notice.
The patients in their private practice also didn't have it diagnosed until they were in their 30s/40s/50s.
 
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