I can't speak to the quality of clinical rotations or research opportunities, but I think reputation wise both are fairly equal. I agree the difference in the weather is negligible, Dayton is maybe a little balmier in the winter months and Toledo gets a bunch of ice and wind but not usually a bunch of snow. But if you live halfway in between I don't expect you'll notice a huge difference in either direction. Toledo, if you count the metro area, does actually get kind of suburban though...isn't the medical school separate from the university main campus, in/near Maumee? It's a nice area though and very walkable, with lots of great trails in the metroparks, which are LOVELY and miles better than the parks systems in even some of the larger cities I've lived in in the region.