Add Cleviprex (Clevidipine) to formulary?

[legaia]

Hi, I was wondering if your institution is adding Cleviprex to formulary?

Cleviprex is an ultrashort acting CCB which is similar to nicardipine. Currently, our institution pays $134.44 for 1 vial (25mg) of nicardipine IV. The usual dose is 5 - 7.5 mg/hr = 3.3 - 5 hrs/vial or $27-40 per hour

Cleviprex costs $125 for a 50 ml vial (0.5 mg/ml) or 25 mg. The usual dose is 4-6 mg/hr = 4- 6.25 hrs/vial or $20-30 per hour.

Our institution used 760 doses of nicardipine last fiscal year.. which would be a savings of 134.44-125 ~ $7000/year + less tech time in preping nicardipine and less iv bag monies. What factors would you consider not switching to cleviprex?

Thanks.

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[legaia]

Hi, I was wondering if your institution is adding Cleviprex to formulary?

Cleviprex is an ultrashort acting CCB which is similar to nicardipine. Currently, our institution pays $134.44 for 1 vial (25mg) of nicardipine IV. The usual dose is 5 - 7.5 mg/hr = 3.3 - 5 hrs/vial or $27-40 per hour

Cleviprex costs $125 for a 50 ml vial (0.5 mg/ml) or 25 mg. The usual dose is 4-6 mg/hr = 4- 6.25 hrs/vial or $20-30 per hour.

Our institution used 760 doses of nicardipine last fiscal year.. which would be a savings of 134.44-125 ~ $7000/year + less tech time in preping nicardipine and less iv bag monies. What factors would you consider not switching to cleviprex?

Thanks.

 

[ItsOverZyvox]

Good topic.

But let's look at Clevidipine little closer. It controls perioperative hypertension in CABG patients better compared to the traditional regimen, Nitroglycerin and/or Nitroprusside, and this is accomplished with no rebound tachycardia common with NTG and Nitroprusside. Of course, in this patient popluation, it is prudent to prevent ADRs. Nicardipine, now generic, is really not a good candidate in perioperative setting due to a slower onset and a longer duration of action.

Look at the cost more closely. The vials are $125 and $250 depending on the size (50ml and 100ml) and the duration of therapy is capped at 1000ml and 24 hours..which means $2,500 per 24 hours.

So, here we have a superior drug with less ADR but sure to eat away at the DRG leaving the hospital with very little gross margin.

What angle can we use to counter detail this drug??

I would like to hear it.

 

[ItsOverZyvox]

Hi, I was wondering if your institution is adding Cleviprex to formulary?

Cleviprex is an ultrashort acting CCB which is similar to nicardipine. Currently, our institution pays $134.44 for 1 vial (25mg) of nicardipine IV. The usual dose is 5 - 7.5 mg/hr = 3.3 - 5 hrs/vial or $27-40 per hour

Cleviprex costs $125 for a 50 ml vial (0.5 mg/ml) or 25 mg. The usual dose is 4-6 mg/hr = 4- 6.25 hrs/vial or $20-30 per hour.

Our institution used 760 doses of nicardipine last fiscal year.. which would be a savings of 134.44-125 ~ $7000/year + less tech time in preping nicardipine and less iv bag monies. What factors would you consider not switching to cleviprex?

Thanks.

God...I hope not. You should be paying $72.56 per vial of generic Nicardipine and just by converting to generic, you should be saving $47,000 per year.

However, I think you should be more concerned about potential increase in cost to actually add Cleviprex to the formulary..

 

[legaia]

God...I hope not. You should be paying $72.56 per vial of generic Nicardipine and just by converting to generic, you should be saving $47,000 per year.

However, I think you should be more concerned about potential increase in cost to actually add Cleviprex to the formulary..

Well, would you add it to your formulary?

 

[ItsOverZyvox]

Well, would you add it to your formulary?

Heart says yes but the head says no..

I don't have a position yet.

 

[stevephhs016]

Sorry, but what does this have to do with residencies and fellowships?

 

[legaia]

If you answer the question, it'll increase the chances of you getting a residency.

 

[RxWildcat]

merged the duplicate threads.