Alk Phosph Production

[chromuffin]

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Is Alk Phos made in bile ducts or hepatocytes?
B&B says bile duct epithelial cells.
My professor, a hepatologist, says hepatocyte canalicular membrane and that it is a misconception that it is made in the bile ducts.

 

[Neferpitou]

All I know is that hepatic ALP is related to bile duct (including intra-hepatic) obstruction. Not sure about the exact function or origin of it.