anybody know why...

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I don't really understand your question, can you be more specific about your thought process?
 
you know, we just covered this not too long ago in our physiology class, and I was left wondering the same thing. Apparently this cholinergic component of the SNS accounts for less that 5% of the post-ganglionic neurons in the SNS. All I know is that the sweat glands that receive this innervation are eccrine glands which are responsible for thermoregulation, while apocrine sweat glands (found in the axilla and circum-anal region) receive adrenergic innervation. As far as WHY, well then your guess is as good as mine
 
Because it is there to confuse you...
 
Actually it all comes down to what sweat glands do, THEY SWEAT> The SNS-PNS system is all based on fight or flight response so what do you do when you are scared, sweat your ass off. Also, what do heart attack patients present with, ANSWER = ridiculous sweating. Heart attacks tend to stimulate the sympathetic trunk and because the heart has visceral innervation you tend not to feel intense focal pain, more visceral dull pain that radiates. When a heart attack stimulates the sympathetics it causes you to sweat. The cosmic joke is that God created sweat glands that dont use norepinephrine, they use acetylcholine.

So what diagnosis do you give to that migrant farm worker who came in sweating, drooling all over himself, and complaining of intense muscle spasms? Well, I would say organo-phosphate poisoning as a result of pesticide exposure, pesticides are usually cholinesterase blockers.
 
Whats up, the above posts are really good. here is a breakdown of some of this stuff just to clear up what uses what:

Parasympathetic
- uses Ach at the ganglionic synapse and at the terminal

Sympathetic:

-It uses Ach at all the ganglionic synapses
- It uses NE at the heart, smooth muscle and gland synapses
- It uses Dopamine for renal, cerebral and mesenteric blood vessel synapses to cause some vasodilation
-It uses Ach for the sweat glands and some skeletal blood vessels synapses
-Uses EPI (80%) and NE(20%) at the adrenal medulla


Somatic: Voluntary muscles

Uses Ach as the primary neurotransmitter here at the neuromuscular junction



later

Omar
 
W222 said:
So what diagnosis do you give to that migrant farm worker who came in sweating, drooling all over himself, and complaining of intense muscle spasms? Well, I would say organo-phosphate poisoning as a result of pesticide exposure, pesticides are usually cholinesterase blockers.

:laugh: Jcdoc17 is in my class, we just took the Pharm final today at Miami... this question was on the exam... almost word for word... freaky! :scared:

The only difference was that the drooling, sweating farmer, came in with a heart rate of like 30 and a BP of 85/40 or something and it didnt mention he was complaining of muscle spasms. Treatment? ATROPINE! 😎
 
LOL, we had a question like that in one of our biochem exams........don't forget your 2-PAM
 
jcdoc107 said:
cholinergic nerves to sweat glands are found in the sympathetic nervous system?

Because it just is. Do not question why. Probably to help cool you down as you expend a lot of energy/heat during sympathetic reaction.

There's Frey's syndrome where things can get cross-linked and cause gustatory sweating.

But everyone knows the only real important thing for you to know is which one points and which one shoots! =D
 
I don't know why, but it's pretty cool because it can result in gustatory sweating after parotidotmy.

Anka
 
I was just about to post the same thing, I guess you beat me to it.

Answer to original post is simple, sweat glands are physically connected to the SNS even though they are cholinergic, to help remove some of the heat generated by sympathethic activity, think "flight or fight response (increased HR, Vasoconstriction and Vasodilation etc)"

No more Pharm, No more Physiology. yeah yeah yeah

Call me crazy but I ACTUALLY enjoyed this last module, studying mundane drug name in pharmacology, helped me realize how much s@#$ I can stuff in my brain.


Arsenic810 said:
:laugh: Jcdoc17 is in my class, we just took the Pharm final today at Miami... this question was on the exam... almost word for word... freaky! :scared:

The only difference was that the drooling, sweating farmer, came in with a heart rate of like 30 and a BP of 85/40 or something and it didnt mention he was complaining of muscle spasms. Treatment? ATROPINE! 😎
 
jcdoc107 said:
cholinergic nerves to sweat glands are found in the sympathetic nervous system?

ah thats easy... to stimulate the muscarinic sweat gland receptors, how else ya supossed to do it?
 
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