This actually happened to me last year! I got acceptances from Penn (IS), Missouri, and Wisconsin and was wait-listed at my first choice, NC State along with fifty other unranked OOS students. After writing NC State a letter of intent regarding my status on the waitlist, I narrowed my choice down to Missouri and Wisconsin and was able to visit Wisconsin for an open house for accepted students. After being offered some scholarship money and having a great experience there, I accepted the offer and began searching for housing, thinking about moving, etc. I got a call from NC State about two weeks after this telling me I was off the waitlist and would have the weekend to decide - eek! The boy and I rushed down for a 36 hour visit to tour the school and have a look at the area before making the choice I really wanted to make since turning in my VMCAS. I accepted at NC State that Monday and wrote a detailed letter to Wisconsin outlining my regret and my reasons for withdrawing my acceptance offer (tuition cost, significant other's grad school plans, family proximity) and followed it up with a phone call in a few days. No hard feelings and they were very understanding - plus some other lucky student got to attend an awesome vet school in my place! 👍