Step I BB AND REFLEX HTN

[1NYCDOC]

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Beta blockers is given in HTN to block renin. Why dont you get reflex HTN with BB, and worsen the HTN ?

 

[Jabbed]

Beta blockers is given in HTN to block renin. Why dont you get reflex HTN with BB, and worsen the HTN ?

Trick question: you do get rebound HTN, but it has little to do with renin and more to do with rebound inotropic effects.

ß-selective ß blockers are not used routinely for isolated treatment of HTN. The primary benefit is preventing reflex tachycardia when combined with a vasodilator. The ones you use for BP control are Labetalol/carvedilol, which are mixed (α-ß) and nebivolol, which has a NO-activating property that leads to vasodilation. Even then, they are not first-line.

 

[1NYCDOC]

Trick question: you do get rebound HTN, but it has little to do with renin and more to do with rebound inotropic effects.

ß-selective ß blockers are not used routinely for isolated treatment of HTN. The primary benefit is preventing reflex tachycardia when combined with a vasodilator. The ones you use for BP control are Labetalol/carvedilol, which are mixed (α-ß) and nebivolol, which has a NO-activating property that leads to vasodilation. Even then, they are not first-line.

CORRECT , BUT, why is Metoprolol often prescribed with ace/arbs, opposed to carvedilol/labetelol ? TIA

 

[Jabbed]

CORRECT , BUT, why is Metoprolol often prescribed with ace/arbs, opposed to carvedilol/labetelol ? TIA

Metoprolol + ACEi is for structural heart disease rather than isolated hypertension. The premise is to prevent further hormonal/adrenergic remodeling.